Laboratory of Cell Morphogenesis
The laboratory is part of the Department of Experimental Plant Biology at the Faculty of Sciences, Charles University, and is closely linked to the Laboratory of Cell Biology at the Institute of Experimental Botany, ASCR. The main focus of our research is on molecular mechanisms of plant cell polarity.
(who is who in the lab)
(a selection of recent works)
(including links to ¶ome useful free software tools by others and ourselves)
Since plant cells are enclosed in a rigid cell wall, they cannot migrate. All plant mophogenesis, both on the level of a single cell and on the multicellular body level, must thus be accomplished by oriented cell division and polarized cell growth. Both of these processes are critically dependent on the cells´ ability to deliver compounds and structures (such as, e.g., secretory vesicles) to distinct parts of its surface (or distinct intracellular compartments). Polarized exocytosis is also unseparable from membrane recycling, and thus from the context of the whole endomembrane system.
The image (from ®árský et al. 2009) presents a summary of known signalling proteins participating in the establishment and function of an activated cortical domain (ACD) - an area of the cell surface engaged in active membrane turnover.
The laboratory focuses mainly on evolutionarily conserved proteins and protein complexes participating in polarised exocytosys and cytoskeletal organisation, namely:
Our main model systems are Arabidopsis thaliana and Physcomitrella patens plants, with other systems (such as tobacco pollen) employed in certain studies..